A festive dessert
Preheat the oven to 350F. Cut the panettone into 1-inch cubes. Place the cubes in a 9x13 baking pan.
In a medium bowl, whisk the eggs and sugar until combined.
Add the half and half, orange zest, and liqueur if using, and whisk again.
Add the egg mixture to the pan with the panettone, submerging the cubes. Let stand for 10 minutes. Bake for 50-60 minutes until golden brown and set. Serve warm or at room temperature.